Application of online chromatography
to enable Continuous Manufacturing
11th February 2021 at 3pm
Since the early
2000s with the FDA initiative technologies continue to evolve to meet the needs
of better process analytical technology tools combined with their integration
into continuous manufacturing. With improvements in technologies the scientists
now have at their disposal better information about their process. When looking
for process learning, understanding and knowledge the analyst has much more
information regarding the critical process parameters and critical quality
attributes of their process. With all this information now, a fully controlled
in automated system can be deployed into manufacturing to monitor in control a
higher quality manufacturing product.
From the laboratory one of the predominant and critical technologies has
been high performance liquid chromatography. Chromatography utilizes many tools
that will provide the analyst with critical information regarding their
process. When you combined sensitivity in resolution the chromatographic
information yields much more highly quantitative information. The good news
this technique will give you more information about your sample then many of
the other techniques available however it is much slower and complicated as
compared to many of the other tools that are at the analyst disposal.
will talk about the advances in separations technology both in the laboratory and
being integrated into the manufacturing process. We will look at examples in
both API synthesis as well as bioprocessing and the lessons learned in process
development. In addition, we will look at the other critical department's that
need to be part of this learning process and how the appropriate tools can be
deployed into manufacturing. The webinar will discuss various sampling and
handling challenges, various separations tools and detector technology, and
finally the many s/w packages that are needed for analysis, communication, and
The webinar will be presented by Ernie Hillier, EJH
Consulting and Martin Warman, Martin Warman Consultancy and CPACT Associate Member.
The webinar will last no longer than one hour.
To register please contact Christine.firstname.lastname@example.org